As a member of this team, Dr. Mishra is involved in the development of novel genomic analysis tools by integrating molecular biology, chemistry, hardware, and software components. And supports the development of high-quality, robust new products in both cutting-edge research and in vitro diagnostics (IVD).

During this stint, Dr. Mishra was involved in understanding brain disorders, one cell at a time. In her position, she attempted to decode epigenetic basis of neuropsychiatric illness by developing and employing integrative approaches at the interface of single-cell epigenetics, gene regulation, and bioinformatics. She aimed to engineer cellular circuits and advance the landscape of precision medicine by leveraging her expertise in cutting-edge sequencing and genome editing technologies.

At this time, Dr. Mishra handled different projects, investigating virus tactics in adapting to their hosts, host immune response to infection, and capturing the dynamics of both host and pathogen transcriptional and translational alterations in infected tissues. By developing a multi-omics computational pipeline, her team published the novel plausible function of a group of undefined genes that are dysregulated during viral infection and further rendered evidence on a candidate transcription factor role in the viral innate immunity using a worm-virus model system. Her other major project that was focused on understanding the virus's role in brain function, behavior, and disease via microbiota remodeling and shifting in animal models, presented a striking clue on the alteration of key metabolites and neurotransmitters eventually leading to neuronal Attention Deficit Hyperactivity Disorder (ADHD) in humans.

During this short term, Dr. Mishra worked in a project at the cross-road of the genome editing and metabolomics field applied to tomato plants. As a member of that research team, she developed a qPCR based high resolution melting curve assay and characterized CRISPR-CAS9 generated tomato lines.

During her doctoral research, Dr. Mishra studied the genetics of sennosides compound, a naturally produced drug from the Senna alexandrina (senna) medicinal plant, and popularly sold as an over-the-counter branded senna drug, employed for its laxative action. Briefly, by evaluating senna genome, she characterized novel molecular barcodes and developed multiplexed PCR and qPCR sequencing assays and chemical tools for identification and authentication of senna raw drugs and its finished products in pharmaceutical market. Moreover, by modeling secondary structures of the nuclear ribosomal (nrRNA) gene clusters, she discovered and published a novel motif to characterize senna genome. Additionally, through the chemical study, she developed a reversed-phase high-performance liquid chromatography (RP-HPLC) method for precise quantification of sennosides compound in senna extracts.

During this period, Dr. Mishra worked in a multi-organizational TKDL (Traditional Knowledge Digital Library) project. Applying data mining tools, she contributed to development of TKDL database, documenting the comprehensive information on 2600 medicinal & aromatic plants and their formulations used in Indian systems of medicine classified as per international patent systems.